The infection related to hypertensive intracranial hemorrhage
Conditions
Interventions
Treatment Group:Metoprolol(50mgBID)or combined with other types of antihypertensive drugs
control group:Non-beta-blocking antihypertensive drugs
Sponsors
the First People's Hospital of LongQuanyi District
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Acute onset, the intracranial hemorrhage is confirmed by head CT or MRI. 2. Clear history of hypertension or admission blood pressure >140/100mmHg. 3. Patient informed consent.
Exclusion criteria
Exclusion criteria: 1. The time arriving at hospital after the onset exceed 24 hours. 2. The intracranial hemorrhage caused by non-hypertensive factors is confirmed by CTA or DSA. 3. With a significant history of aspiration,asthma,COPD with acute onset,asthma attacks, and active pulmanary infection confirmed by clinically and laboratory evidence. 4. Requiring antibiotic treatment because of the severe infection. 5. Patients who need surgery or died shortly after admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PCT;CRP;IL-10; | — |
Secondary
| Measure | Time frame |
|---|---|
| WBC;N%; | — |
Countries
China
Contacts
Public ContactChen Fang
Neurosurgery Department of the First People's Hospital of LongQuanyi District
Outcome results
None listed