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Clinical Observation for Pulsed Radiofrequency and Short-term Spinal Cord Electrical Stimulation in the Treatment of Subacute Herpes Zoster Neuralgia:A Randomized, Controlled, Double-blind Clinical Trial

Clinical Observation for Pulsed Radiofrequency and Short-term Spinal Cord Electrical Stimulation in the Treatment of Subacute Herpes Zoster Neuralgia:A Randomized, Controlled, Double-blind Clinical Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900022586
Enrollment
Unknown
Registered
2019-04-17
Start date
2019-04-26
Completion date
Unknown
Last updated
2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

herpetic neuralgia

Interventions

experimental group:spinal cord electrical stimulation
control group:pulse radiation frequency

Sponsors

The First Affiliated Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Aged > 60 years, male or female; 2. Herpes zoster was definitely diagnosed, and there were typical herpes zoster neuralgia (Practical Pain Science, Liu Yanqing, Cui Jianjun, 2013 edition). 3. The onset site of herpes zoster was thoracic and lumbar segments (T1-L5). 4. The onset time was about 1 month, but less than 4 months. 5. Pain persisted one week after three consecutive oral gabapentin doses (1800 mg/d) three times a day, and the daily average VAS (early, mid, late and before bedtime) was still more than 4 points. 6. Volunteer to participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Disagree with the treatment of this experiment; 2. Cannot tolerate the operation of epidural catheter/electrode; 3. Pregnant women. 4. Patients with severe heart, brain, liver and body diseases who cannot tolerate minimally invasive surgery; 5. Patients with abnormal coagulation function; 6. Patients with severe psychiatric or other illnesses who cannot correctly score pain or objectively describe symptoms; 7. Patients who cannot be followed up on schedule; 8. Allergic to related drugs and excipients.

Design outcomes

Primary

MeasureTime frame
pain score;

Secondary

MeasureTime frame
Quality of life score;

Countries

China

Contacts

Public ContactWan Chengfu
doctor_wanty@163.com+86 13704026541

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026