Clinical evaluation of autogenous keratinized mucosa combined with xenogeneic collagen matrix in repairing severe keratinized gingiva defect

Clinical evaluation of autogenous keratinized mucosa combined with xenogeneic collagen matrix in repairing severe keratinized gingiva defect: a prospective clinical trial

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900022575

Enrollment

Unknown

Registered

2019-04-17

Start date

2018-11-01

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

defect of peri-implant soft tissue

Interventions

experimental group :autogenous keratinized mucosa combined with xenogeneic collagen matrix

control:free gingival graft

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The buccal keratinized gingiva was less than 2 mm and the grafting area was larger than 2 teeth. 2. No soft tissue increment was performed at the test site. 3. Aged > 18 years. 4. Good health. 5. Good oral hygiene. 6. Be able to review regularly.

Exclusion criteria

Exclusion criteria: 1. Allergy to collagen; 2. Systemic diseases: diabetes mellitus, malignant tumors, diseases affecting connective tissue metabolism, radiotherapy and chemotherapy; 3. Uncontrolled periodontal disease; 4. Pregnant or lactating women; 5. Smoking > 10 cigarettes per day; 6. Other cases that do not meet the requirements of implant therapy.

Design outcomes

Primary

Measure	Time frame
width of keretinized mucosa;	—

Countries

China

Contacts

Public ContactLin Ye

Peking University, School of Stomatology

yorcklin@263.net+86 010-82195341

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 21, 2026