Comparison of oxycodone versus morphine in the treatment of patients with severe cancer pain: a randomized controlled trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900022566

Enrollment

Unknown

Registered

2019-04-16

Start date

2019-04-18

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer pain

Interventions

oxycodone:30 mg oxycodone as the starting dose

morphine:Immediate release morphine titration

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 years; 2. Patients with pathological or cytological diagnosis of tumor; 3. Pain intensity (NRS) score for severe pain; 4. Be conscious; be able to understand the doctor's medication plan guidance; 5. Opioid intolerance patients.

Exclusion criteria

Exclusion criteria: 1. Pregnancy or lactation; 2. Pain crisis or other oncology emergency; 3. Contraindications to strong opioids; 4. Patients with severe liver and kidney function (ALT/AST/creatinine/urea nitrogen is 3 times higher than the upper limit of normal). 5. History of drug or alcohol abuse.

Design outcomes

Primary

Measure	Time frame
NRS;	—

Countries

China

Contacts

Public ContactHu Guangyuan

huguangyuan2018@sohu.com+86 13098834328

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026