Precise diagnosis of acute chest pain based on new biomarkers: a multicenter prospective cohort study

Precise diagnosis of acute chest pain based on new biomarkers

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900022543

Enrollment

Unknown

Registered

2019-04-16

Start date

2019-08-01

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute non-traumatic chest pain

Interventions

Gold Standard:1)AAD: aortic CTA

2) AMI: coronary angiography

3) PE: CTPA.

Index test:Mass&#32

spectrometry&#32

technology

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. All kinds of nontraumatic ACP diagnosed by gold standard: 1)acute aortic dissection (AAD) diagnosed by aortic computed tomography angiography (CTA); 2)acute myocardial infarction (AMI) diagnosed by coronary angiography; 3) pulmonary embolism (PE) diagnosed by computed tomography pulmonary artery angiography (CTPA); 2. Patients with less than 24 hours of symptom onset.

Exclusion criteria

Exclusion criteria: 1. history of cancer; 2. infectious diseases within 1 month; 3. autoimmune diseases; 4. diabetes mellitus; 5. pregnant women; 6. repeated visits at selected time.

Design outcomes

Primary

Measure	Time frame
Protein markers;Metabolic marker;Lipid marker;Death;Polypeptide marker;Gene maker;Intestinal microbiological marker;	—

Secondary

Measure	Time frame
Cardiovascular adverse events;	—

Countries

China

Contacts

Public ContactZhi Wan

West China Hospital, Sichuan University

303680215@qq.com+86 28-85422461

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026