Effects of vitamin D therapy on composition and cardiovascular risk factors in patients with Type 2 diabetes mellitus

The correlation between vitamin D level and diabetic macroangiopathy, is vitamin D therapy useful?

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900022515

Enrollment

Unknown

Registered

2019-04-14

Start date

2019-04-15

Completion date

Unknown

Last updated

2019-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

Treatment group:Different doses of vitamin D3 were given according to the level of 25OHD + Routine treatment of diabetes mellitus

Control group:Routine treatment of diabetes mellitus

Eligibility

Sex/Gender

All

Age

30 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Volunteer as the subject who will sign informed consent; 2. Aged 30 to 65 years; 3. Met the diagnostic criteria for diabetes established by WHO in 1999.

Exclusion criteria

Exclusion criteria: 1. Patients with hypercalcemia (serum calcium higher than 2.6 mmol/L) or with severe heart, brain, liver, kidney and hematopoietic system diseases and psychosis; 2. Pregnancy, lactation women, allergic constitution; 3. Drugs affecting bone metabolism are currently being taken.

Design outcomes

Primary

Measure	Time frame
25(OH)D;Insulin;Carotid intima-media thickness;	—

Secondary

Measure	Time frame
glucose;serum lipid;glycosylated hemoglobin;Superoxide dismutase;malondialdehyde;Glutathione peroxidase;Total antioxidant capacity;Interleukin-6;Tumor necrosis factor alpha;Interleukin-2;nitric oxide;	—

Countries

China

Contacts

Public ContactHuang Jinhua

Beijing Zhongguancun Hospital

huangjinhua@yeah.net+86 13910032406

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026