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The role of gallbladder-preserving surgery combined with Chinese medicine in the treatment of gallstone diseases.

The role of Laparoscopic gallbladder-preserving surgery combined with intraoperative choledochoscopy and postoperative Chinese medicine in the treatment of gallstone diseases

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900022482
Enrollment
Unknown
Registered
2019-04-13
Start date
2015-03-01
Completion date
Unknown
Last updated
2019-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gallbladder stone

Interventions

Case series:no

Sponsors

First Affiliated Hospital of Medical College of Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients aged 14 to 70 years old; 2. The gallbladder has function (intraoperative choledochoscopy: the gallbladder duct is unobstructed and the gallbladder mucosa is basically normal); 3. Assessment of patient safety and tolerance Hypertension, diabetes mellitus and cardiac insufficiency should be evaluated by relevant departments; 4. The patient is willing to retain the gallbladder. After informing the risk of recurrence, gallbladder-preserving lithotripsy can also be performed; 5. Patients with complete clinical data during hospitalization; 6. Postoperative follow-up can be done by telephone, etc.; 7. Postoperative patients who are willing to take Chinese medicine orally according to the research requirements and are regularly reexamined; 8. Filled gallbladder stones: After removal of gallbladder stones, the gallbladder duct is unobstructed, the bile can refill the gallbladder, showing a nearly normal gallbladder, and the gallbladder wall is soft and the tissue level is clear, so gallbladder-preserving operation is feasible; 9. White bile and gallbladder atrophy were found during the operation: the empty gallbladder was observed during the operation. After removing the gallstone, gallbladder duct bile flowed into gallbladder unobstructed, gallbladder filled with gallbladder showed nearly normal gallbladder, and gallbladder wall tissue was soft and clear. Under?the?circumstances gallbladder-preserving operation was feasible; 10. Intracavity septation of gallbladder was found during operation: the diameter of septal foramen was greater than 5 m, and the mucosa was normal. The thickness of gallbladder wall was less than 5 m. The diameter of the septum is less than 5 m, and the proximal gallbladder is more than 5 cm. Partial distal cholecystectomy is feasible. Otherwise, cholecystectomy should be performed.

Exclusion criteria

Exclusion criteria: 1. Preoperative complications of special digestive system diseases, such as digestive tract reconstruction; 2. Preoperative imaging examinations revealed diseases of extragallbladder biliary tract system, such as choledochal cyst, intrahepatic bile duct stones and high confluence of biliary and pancreatic ducts; 3. Preoperative imaging examination showed that giant duodenal diverticulum compressed common bile duct; 4. Preoperative patients with malignant tumors, diabetes mellitus and autoimmune diseases need long-term drug treatment;l 5. Suspicious patients with incomplete data; 6. Patients with gallbladder malignant tumors were suspected by preoperative imaging; 7. Intraoperative cholangioscopy was performed in patients suspected of malignant transformation of gallbladder mucosa; 8. Preoperative imaging showed gallbladder atrophy and disappearance of gallbladder cavity; 9. Patients with gallbladder xanthogranuloma or gallbladder-digestive tract fistula; 10. Two weeks after operation, B-mode ultrasonography of hepatobiliary and pancreas revealed residual gallstones with a maximum diameter of more than 1 cm; 11. Removal of new malignant tumors after surgery; 12. Patients who died of unknown causes after operation were excluded from the study; 13. Acute and subacute cholecystitis with gallstones.

Design outcomes

Primary

MeasureTime frame
recurrence rate;

Countries

China

Contacts

Public ContactFuchun Yang

First Affiliated Hospital of Medical College of Zhejiang University

yangfc003@zju.edu.cn+86 13606521711

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026