Lumbar spinal stenosis, lumbar disc herniation, lumbar spondylolisthesis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who need surgery for spinal diseases such as lumbar spinal stenosis, lumbar disc herniation, and lumbar spondylolisthesis; 2. Aged 18 to 75 years; 3. ASA I-II;
Exclusion criteria
Exclusion criteria: 1. Patient who refuses; 2. Coagulation dysfunction; 3. Neuropathy; 4. Allergy to local anesthetic drugs; 5. Puncture site infection; 6. Severe liver and kidney dysfunction; 7. Severe pulmonary dysfunction; 8. Mental illness; 9. History of substance abuse; 10. Recent history of acute or chronic pain; 11. Emergency surgery; 12. Pregnancy; 13. Morbid obesity (BMI=35 Kg/m2); 14. History of aspirin asthma or nonsteroidal drug allergy; 15. Previous surgical history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Morphine consumption;NSAIDs consumption;VAS score;TNF-alpha, IL-6, IL-10, HMGB1, Lymphocyte, IFN-r, IL-4, IL-17, IL-35;QoR-15 score; | — |
Countries
China
Contacts
Guangdong Second Provincial General Hospital