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The study for the correlation between the serum P53 and mir-199a-5p and their effect to the urinary albumin excretion rates in type 2 diabetes mellitus patients

The study for the correlation between the serum P53 and mir-199a-5p and their effect to the urinary albumin excretion rates in type 2 diabetes mellitus patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900022452
Enrollment
Unknown
Registered
2019-04-11
Start date
2019-04-22
Completion date
Unknown
Last updated
2019-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes mellitus

Interventions

M0 Group:None
M1 Group:None
M2 Group:None
M3 Group:None

Sponsors

First Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: ? population who are diagnosed as T2DM or normal; ? aged 30 to 70 years.

Exclusion criteria

Exclusion criteria: ? in the last 3 months there are no acute diabetic complications, such as diabetic hyperosmotic coma ,diabetic ketoacidosis, etc; ? with cerebrovascular disease, liver function damage, infectious disease or history of malignant tumor; ? with stress conditions, such as infection, surgery, trauma,etc; ? special physical conditions, such as pregnancy and lactation; ? patients in L-UAlb+HP group were treated by ACEI or ARB.

Design outcomes

Primary

MeasureTime frame
mir-199a-5p;P53;Urinary albumin to creatinine ratios;—

Secondary

MeasureTime frame
fasting plasma insulin;fasting plasma glucose;HOMA-IR;Caveolin-1;early growth response protein-1;—

Countries

China

Contacts

Public ContactZhou Yang

First Hospital of China Medical University

18640098256@163.com+86 18640098256

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026