Cerebral small vascular disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Meet the diagnostic criteria of cranial MRI for cerebrovascular disease (including subcortical infarction, lacunar infarction, white matter hyperintense signal, microbleeding and cerebral atrophy); has stable health status, can activate independently, can understand and correctly answer questions and assist in completing questionnaires; and has informed consent to the research and voluntary participation.
Exclusion criteria
Exclusion criteria: Within six months, stroke and surgery patients who affected daily life activities occurred; cognitive impairment and dementia caused by other factors, such as large area cerebral infarction or cerebral hemorrhage, epilepsy, encephalitis, brain tumors, intracranial demyelination lesions, history of brain trauma, normal hydrocephalus, multiple sclerosis, hypothyroidism, Alzheimer's disease, etc. combined with New York Heart Disease Grading (NYHA). Patients with grade II or above; patients with severe liver and kidney diseases and malignant tumors; acute infections, autoimmune diseases, osteoarthritis, major organ failure, short-term life-threatening diseases; patients and followers who could not cooperate with the completion of the evaluation; patients who were excluded from magnetic resonance examination contraindications, or who could not cooperate with the completion of magnetic resonance examination for other reasons (e.g. claustrophobia, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| frailty, cognitive frailty; | — |
Countries
China
Contacts
Affiliated Huanhu Hospital of Nankai University