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Effect of rehabilitation intervention on the incidence and risk factors of frailty and cognitive frailty in patients with cerebral small vessel disease

Effect of rehabilitation intervention on the incidence and risk factors of frailty and cognitive frailty in patients with cerebral small vessel disease

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900022427
Enrollment
Unknown
Registered
2019-04-10
Start date
2019-04-08
Completion date
Unknown
Last updated
2020-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral small vascular disease

Interventions

frailty group vs. pre-frailty group vs.non frailty group:rehabilitation intervention

Sponsors

Affiliated Huanhu Hospital of Nankai University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Meet the diagnostic criteria of cranial MRI for cerebrovascular disease (including subcortical infarction, lacunar infarction, white matter hyperintense signal, microbleeding and cerebral atrophy); has stable health status, can activate independently, can understand and correctly answer questions and assist in completing questionnaires; and has informed consent to the research and voluntary participation.

Exclusion criteria

Exclusion criteria: Within six months, stroke and surgery patients who affected daily life activities occurred; cognitive impairment and dementia caused by other factors, such as large area cerebral infarction or cerebral hemorrhage, epilepsy, encephalitis, brain tumors, intracranial demyelination lesions, history of brain trauma, normal hydrocephalus, multiple sclerosis, hypothyroidism, Alzheimer's disease, etc. combined with New York Heart Disease Grading (NYHA). Patients with grade II or above; patients with severe liver and kidney diseases and malignant tumors; acute infections, autoimmune diseases, osteoarthritis, major organ failure, short-term life-threatening diseases; patients and followers who could not cooperate with the completion of the evaluation; patients who were excluded from magnetic resonance examination contraindications, or who could not cooperate with the completion of magnetic resonance examination for other reasons (e.g. claustrophobia, etc.)

Design outcomes

Primary

MeasureTime frame
frailty, cognitive frailty;

Countries

China

Contacts

Public ContactMu Lei

Affiliated Huanhu Hospital of Nankai University

mulei75414663@126.com+86 13404845890

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026