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Cardiovascular risk assessment and early intervention studies based on enviromental and epigenetic inheritance in Sichuan

Environmental and epigenetic factors and early intervention of hypertension and coronary heart disease in Sichuan

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900022374
Enrollment
Unknown
Registered
2019-04-08
Start date
2019-04-08
Completion date
Unknown
Last updated
2019-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension

Interventions

Experimental group:Disease management based on the early intervention platform on the Internet
control group:traditonal management by family doctor

Sponsors

West China Hospital of Sichuan university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. essential hypertension,and the systolic pressure was measured greater than 140 at 3 times in a row in doctor's office; 2. Aged 40-70 years; 3. have smartphone and can use it in order to be followed by doctors; 4. the score of morisky is 4-6; 5. signed a contract with a family doctor at least for one year; 6. signing and willing to participate in this project, and giving consent to accept the diagnosis and treatment of hypertension at the designated medical institutions, and re-referred to superior medical institutions when necessary; will not drop out due to the long-term leave, going abroad or other reasons during the 1 year.

Exclusion criteria

Exclusion criteria: 1.secondary hypertension, hypertension emergency; 2. with type 1 diabetes; type 2 diabetes mellitus with acute metabolic disorder;secondary dyslipidemia patients (secondary to patients with type 2 diabetes not included); 3. acute myocardial infarction (<3 months) and stroke (<3 months) acute phase; 4. patients with chronic renal disease (eGFR <60ml/min/1.73m2 or urine albumin/creatinine ratio = 30); 5. pregnant women and nursing mothers; difficult to cooperate (psychiatric illness, hearing difficulty, or physical incapacitation); 6. to combine serious diseases with a life expectancy of less than one year; 7. healthcare provider; 8. participators in a similar project in the last 3 months; 9. data of blood pressure from doctor's less than 3 times.

Design outcomes

Primary

MeasureTime frame
Blood pressure;total cholesterol;fasting blood-glucose;waistline;score of MMAS-8;hipline;

Secondary

MeasureTime frame
Uric acid;creatinine;AST;routine urine test;electrocardiogram;carotid artery ultrasound;ambulatory blood pressure;electrolytic;creatine kinase;frequency of follow-up;the times of having blood test;

Countries

China

Contacts

Public ContactLiao Xiaoyang

West China Hospital, Sichuan University

6258801359@qq.com+86 18980601359

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026