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Study for Posner-Schlossman syndrome

Study for topical anti-cytomegalovirus treatment on Posner-Schlossman syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900022340
Enrollment
Unknown
Registered
2019-04-06
Start date
2019-05-01
Completion date
Unknown
Last updated
2019-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Posner-Schlossman syndrome

Interventions

Group 1:By ganciclovir for 3 months
Group 2:By ganciclovir for 12 months
Group 3:traditional steroid treatment

Sponsors

Eye and ENT Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Posner-Schlossman syndrome patients, with recurrent elevated intraocular pressure higher than 21mmHg during attack periods and normal intraocular pressure between attack periods, very mild inflammation within anterior chamber, presence of kp and open angle. The intraocular pressure, visual field and optic disc of the unaffected eye is normal; 2. Cytomegalovirus positive in aqueous humor; 3. Aged older than 18 years; 4. Consented to attend the study.

Exclusion criteria

Exclusion criteria: 1. Patients with primary glaucoma or elevated intraocular pressure due to other causes; 2. Other ocular disease, including retinal disease, corneal disease, ocular trauma or inflammation; 3. Patients who has received topical or systemic antivirus treatment before admission; 4. Patients who has underwent anti-glaucoma surgery before admision; 5. Allergic to ganciclovir; 6. Existence of hepatorenal insufficiency or hematological diseases.

Design outcomes

Primary

MeasureTime frame
intraocular pressure;inflammation;recurrent times;

Countries

China

Contacts

Public ContactKong Xiangmei

Eye and ENT Hospital of Fudan University

kongxm95@163.com+86 13817890921

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026