The Pathogenesis of Large Intestine Damp-heat Syndrome in Ulcerative Colitis Based on Pathways Related with Microbiome-Gut-Brain Axis

Pathogenensis of Intestinal Damp-heat Syndrome in Ulcerative Colitis Based on Pathways Related with Microbiome-Gut-Brain Axis

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900022285

Enrollment

Unknown

Registered

2019-04-03

Start date

2019-04-01

Completion date

Unknown

Last updated

2019-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative Colitis

Interventions

UC:Nil

HC:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Those who meet the diagnostic criteria of Western medicine and TCM syndromes for mild or moderate UC in active stage, or those who routinely screen for physical examination; 2. The lesion does not exceed sigmoid colon; 3. Aged 18 to 65 years; 4. agree to participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Complicated with severe complications or history of abdominal surgery, such as toxic megacolon, intestinal obstruction, stricture, perforation and canceration; 2. Complicated with serious diseases such as hematopoietic system, liver, kidney and endocrine system (diabetes, metabolic syndrome, cancer, etc.) or psychiatric diseases; 3. alcoholism or drug addiction; 4. Pregnancy or lactation; 5. Participate in other clinical research 6. used antibiotics within past 3 months; used gastrointestinal motility drugs, acid inhibitors, microecological agents or immunosuppressants in past 3 weeks.

Design outcomes

Primary

Measure	Time frame
cytokine;intestinal microbiome;Metabonomics;	—

Countries

China

Contacts

Public ContactJianhua Zhen

Beijing University of Chinese Medicine

2018011012@bucm.edu.cn+86 17801084685

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026