Effect of different doses of dexmedetomidine on sevoflurane MAC in adult laryngeal mask placement

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900022281

Enrollment

Unknown

Registered

2019-04-03

Start date

2019-05-01

Completion date

Unknown

Last updated

2019-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gallstone

Interventions

D2:Sevoflurane induction (dexmedetomidine 1µg/kg)

DO:Sevoflurane induction (dexmedetomidine 0µg/kg)

D1:Sevoflurane induction (dexmedetomidine 0.5µg/kg)

D3:Sevoflurane induction (dexmedetomidine 1.5µg/kg)

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: ASA I-II grade; age 20-60 years; BMI = 28kg/m2.

Exclusion criteria

Exclusion criteria: 1. Suspected difficult airway; 2. obesity; 3. With chronic obstructive pulmonary disease; 4. With history of congenital heart disease; patients with acute upper respiratory tract infection. 5. With hypertension; 6. With coronary heart disease; 7. With family history of malignant hyperthermia; 8. With contraindications for laryngeal mask placement.

Design outcomes

Primary

Measure	Time frame
End-tidal sevoflurane concentration;	—

Countries

China

Contacts

Public ContactXiaolin Yang

North Sichuan Medical College

yang_xl_yang@126.com+86 13990826183

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026