The biomarkers of different phenotypes of chronic obstructive pulmonary disease

Screen molecular typing markers of COPD and construct early diagnosis model based on multi omics technology

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900022271

Enrollment

Unknown

Registered

2019-04-02

Start date

2017-10-08

Completion date

Unknown

Last updated

2019-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease

Interventions

Gold Standard:After inhalation of bronchodilator, COPD was diagnosed according to GOLD criteria.

Index test:Multi&#32

omics&#32

technology.

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: For COPD patients:1)Aged at least 18 years; 2)After inhalation of bronchodilator, COPD was diagnosed according to GOLD criteria. For control subjects:1)Aged at least 18 years; 2)Physical examination and routine laboratory examination are normal; 3)Chest radiography is normal; 4)Normal lung function: FVC, FEV1, FEV1/FVC, TLC, DLCO; 5)Normal electrocardiogram; 6)No drugs were used to treat lung diseases within 6 months.

Exclusion criteria

Exclusion criteria: For COPD patients and control subjects:1) Chronic lung diseases, such as asthma;2) Acute exacerbation of pulmonary disease occurred within 3 months; 3) History of malignant tumors.

Design outcomes

Primary

Measure	Time frame
transcriptomics;proteomics;metabonomics;	—

Countries

China

Contacts

Public ContactFuqiang Wen

West China Hospital of Sichuan University

wenfuqiang.scu@gmail.com+86 18980601258

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026