azoospermia with varicocele
Conditions
Interventions
1:anastrozole
2:M-Varicocele ligation
3:Anastrozole and M-Varicocele ligation
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1) aged 18-45 years, male; 2) volunteer to participate in the clinical study. Before the study, the subjects sign a written informed consent; 3) patients with NOA and VC who come to our hospital for treatment; 4) clinical VC was diagnosed by physical examination, and the criteria were as follows: level I: only accessible after Valsaval action;Level II: standing position can touch, but not visible;Level III: visible and palpable by standing position examination; 5) B ultrasound of scrotum conforms to VC performance.
Exclusion criteria
Exclusion criteria: 1) patients with secondary VC; 2) patients with recurrent VC; 3) patients with a history of surgery in the inguinal region on the affected side; 4) patients with a history of lateral scrotal surgery; 5) patients with urinary and reproductive system infection; 6) azoospermia caused by other known diseases or congenital diseases, such as cryptorchidism, creutzfeldt-jakob syndrome, kalman syndrome, Y chromosome microdeletion, etc.; 7) patients who had received AI, hCG, hMG, estrogen receptor antagonist and other drugs affecting the hypothalamic-pituitary-gonadal axis within 4 weeks were excluded; 8) patients with systemic diseases, such as hypertension, diabetes, liver and kidney insufficiency, etc.; 9) patients who cannot be operated on due to various reasons, such as the presence of coagulation dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| semen analysis;Success rate of sperm extraction; | — |
Countries
China
Contacts
Public ContactLi Zheng
Shanghai General Hospital
Outcome results
None listed