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The mechanism of drug-resistant epilepsy based on single cell transcriptome sequencing

The mechanism of drug-resistant epilepsy based on single cell transcriptome sequencing

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900022261
Enrollment
Unknown
Registered
2019-04-02
Start date
2019-05-01
Completion date
Unknown
Last updated
2019-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy

Interventions

Temporal lobe group:Resection
Health control:Nil

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Outpatient and hospitalized patients with epilepsy admitted to our hospital. The diagnosis of epilepsy is defined by the International Association for the Prevention of Epilepsy (ILAE) 2014: (1) at least two non-evoked (or reflexive) episodes, with two episodes separated by more than 24 hours; (2) in the next 10 year, the likelihood of a non-evoked (or reflex) episode and a future episode is comparable to the risk of recurrence after two non-evoked episodes (at least 60%); (3) diagnosis of epilepsy syndrome.

Exclusion criteria

Exclusion criteria: 1. Acute symptomatic epilepsy; 2. psychogenic non-epileptic seizures; 3. individuals can not cooperate with the test; 4. individuals do not agree to participate in the study.

Design outcomes

Primary

MeasureTime frame
lncRNA;—

Countries

China

Contacts

Public ContactDong Zhou

West China Hospital, Sichuan University

zhoudong66@yahoo.de+86 13980008088

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026