esophageal carcinoma
Conditions
Interventions
discontinuing heating when body temperature rises to 35.5 degree)
Sponsors
Shanghai Chest Hospital, Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. ASA I or II patients scheduled to receive curative resection of esophageal carcinoma under general anesthesia; 2. Aged 65-80 years; 3. Duration of the surgery expected to last 2-6 hours; 4. BMI 18-30kg/m2; 5. Meet the inclusion/exclusion criteria for PROTECT
Exclusion criteria
Exclusion criteria: 1. Severe heart, lung, liver and kidney dysfunction; 2. Severe diseases of immune system and endocrine system; 3. End-stage renal diseases requiring dialysis; 4. Major infection (including but not limited to septicemia); 5. Preoperative bronchiectasis, respiratory tract infection, persistent cough and sputum, more secretions in the lungs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lung complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood gas analysis;ICU and hospital stay;Inflammatory mediators;pneumonia score;Other major adverse events prior to patient discharge from hospital;Plasma markers of lung injury;chest drainage volume;Time to chest tube removal;extrapulmonary complication; | — |
Countries
China
Contacts
Public ContactJingxiang Wu
Anesthesiology Department of Shanghai Chest Hospital, Shanghai Jiao Tong University
Outcome results
None listed