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Effect of curcumin combined with probiotics on prevention and treatment in ileal pouchitis after operation of ulcerative colitis.

Effect of curcumin combined with probiotics on prevention and treatment in ileal pouchitis after operation of ulcerative colitis.

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900022243
Enrollment
Unknown
Registered
2019-03-31
Start date
2019-04-01
Completion date
Unknown
Last updated
2019-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ileal pouchitis after operation of ulcerative colitis

Interventions

Experimental group:Curcumin+Probiotics

Sponsors

Tianjin Medical University General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1 Definitely diagnosed as UC and treated with IPAA, the postoperative time is more than 3 months; 2 Patients take probiotics regularly before being selected; 3 Aged 15 years and above; 4 Male or female; 5 Have given consent and the region is able to follow the patient who is treated; 6 Ability to record patients whose responses are answered in a regular follow-up.

Exclusion criteria

Exclusion criteria: 1 Patients with kidney or liver disease, severe cardiovascular disease, chronic pancreatitis, diabetes or gallstones; 2 Postoperative pathology of IPAA surgery indicates that there is cancerous person; 3 Perform other surgical treatments or chemoradiotherapy and targeted therapy in the past 3 months; 4 Patients with laboratory abnormalities indicate anemia (hemoglobin <10), leukopenia, thrombocytopenia, and abnormal blood clotting; 5 Patients with infection, sepsis or pneumonia; 6 Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
Endoscopic score;

Secondary

MeasureTime frame
Blood routine;C-response protein;Fecal calprotectin;

Countries

China

Contacts

Public ContactGang Liu

Tianjin Medical University General Hospital

landmark1509@163.com+86 13389098101

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026