hemiplegia after cerebral infarction
Conditions
Interventions
Paralysis study group (the first scan):true acupuncture stimulation
Paralysis study group (the first scan):sham acupuncture stimulation
Paralysis study group (the second scan):Contrary to the first scan
Healthy control group(the first scan):true acupuncture stimulation
Healthy control group(the first scan):sham acupuncture stimulation
Healthy control group(the second scan):Contrary to the first scan
Sponsors
Dongzhimen Hospital, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Hemiplegia patients test group Diagnostic criteria: Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2014. (1) Patients with cerebral infarction whose course of disease is 1.5 months conform to the diagnostic criteria of cerebral infarction; (2) Right-handed; (3) Between 40 and 75 years of age, both men and women are eligible; (4) In patients with left hemiplegia, the infarct was located in the right basal ganglia and/or the radiation coronal region; (5) The patient has unconscious disorder and the condition is relatively stable; (6) No psychotropic drugs have been taken in the past month; (7) Here is no metal in the body and no contraindication of nuclear magnetic resonance examination; (8) The patient himself or his immediate family members sign the informed consent; 2. Healthy subjects group: (1) Right-handed; (2) Between 40 and 75 years of age, both men and women are eligible; (3) Those who have been proved to be in the range of physical health by physical examination have no organic or significant functional diseases; (4) No family genetic history of mental and nervous system; (5) No research similar to this experiment has been conducted. (6) There were no physical abnormalities (such as cold, headache, cough, etc.) during the experimental period. (7) No excitatory drugs have been taken in the past two months. (8) There are no metal implants in vivo and no contraindications for functional magnetic resonance imaging. (9) Subjects signed the informed consent and volunteered to participate in the experiment.
Exclusion criteria
Exclusion criteria: 1.Hemiplegia patients test group (1)combining with psychiatric disorders or any other serious primary diseases; (2)being pregnant, lactating or menstrual; (3)severe skull anatomical asymmetry or definite lesions being found by MRI scans; (4)taking part in similar neuroimaging test within 1 month. 2.Healthy subjects group: (1)being menstrual, pregnant or lactating; (2)severe skull anatomical asymmetry or definite lesions being found by MRI scans.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| functional connectivity(FC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Voxel-mirrored homotopic connectivity (VMHC);Fractional anisotropy (FA);Voxel-Based Morphometry(VBM);Fugl-Meyer Assessment;hs-CRP; | — |
Countries
China
Contacts
Public ContactYihuai Zou
Dongzhimen Hospital, Beijing University of Chinese Medicine
Outcome results
None listed