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Associations between vitamin D gene polymorphisms and susceptibilities to posttraumatic osteomyelitis in Chinese population

Mechanisms of vitamin D receptor gene polymorphisms in the pathogenesis of posttraumatic osteomyelitis via regulating functions of monocytes-macrophages

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900022186
Enrollment
Unknown
Registered
2019-03-29
Start date
2019-05-01
Completion date
Unknown
Last updated
2019-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Posttraumatic osteomyelitis

Interventions

Patient group:Without intervention
Control group:Without intervention

Sponsors

Nanfang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patient group: Patients with extremity posttraumatic osteomyelitis. Control group: Healthy adults

Exclusion criteria

Exclusion criteria: Patient group:(1) Acute osteomyelitis; (2) With ssystematic systematic or immune system disorders; (3) Received interventional diagnosis and / or treatment that may affect DNA structure previously Control group: With other system disorders previously.

Design outcomes

Primary

MeasureTime frame
Genotype of ApaI (rs7975232);Genotype of BsmI (rs1544410);Genotype of TaqI (rs731236);Genotype of FokI (rs2228570;—

Secondary

MeasureTime frame
Total VD;Serological IL-1ß level;Serological IL-6 level;Serological IL-10 level;Serological IL-12 level;Serological TNF-a level;Serological LL-37 level;—

Countries

China

Contacts

Public ContactYu Bin

Department of Orthopaedics & Traumatology, Nanfang Hospital of Southern Medical University

smuyubin@163.com+86 20-61641746

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026