Pharmacodynamic Study for dexmedetomidine sedation in children

Comparison of ED90 of dexmedetomidine in children with congenital heart disease before and after surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900022180

Enrollment

Unknown

Registered

2019-03-28

Start date

2019-04-01

Completion date

Unknown

Last updated

2019-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital cardiovascular disease

Interventions

Case series:dexmedetomidine was dripped into both nostrils

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: children, aged 0 to 48 months, with congenital heart disease and to be classified as American Society of Anesthesiologists physical status I or II.

Exclusion criteria

Exclusion criteria: 1. known allergy to dexmedetomidine; 2. recent treatment with a-2 adrenergic receptor agonist; 3. renal or hepatic dysfunction; 4. nasal discharges; 5. history of preterm birth.

Design outcomes

Primary

Measure	Time frame
heart rate;Oxygen saturation;respiration rate;	—

Countries

China

Contacts

Public ContactShengfen Tu

Children's Hospital of Chongqing Medical University

tushengfentougao@foxmail.com+86 023-63622984

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026