Clinical and basic research for patients with moderate or severe carotid stenosis

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900022170

Enrollment

Unknown

Registered

2019-03-28

Start date

2019-04-01

Completion date

Unknown

Last updated

2019-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

moderate and severe carotid stenosis

Interventions

Operation group :CEA

non-operation group:conservative treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Unilateral or bilateral carotid atherosclerotic stenosis; 2. Degree of symptomatic carotid stenosis >50%; 3. Degree of asymptomatic carotid stenosis: >70%; 4. The subjects and their families voluntarily signed the informed consent for surgery.

Exclusion criteria

Exclusion criteria: 1. Intracranial hemorrhage within 3 months or fresh cerebral infarction within 2 weeks; 2. Uncontrolled hypertension; 3. Have severe bleeding tendency; 4. Complete occlusion of the diseased side carotid; 5. Patients with intracranial aneurysms cannot be treated in advance or at the same time; 6. Carotid bifurcation high or common carotid artery stenosis below the clavicular plane.

Design outcomes

Primary

Measure	Time frame
Degree of carotid stenosis;Degree of carotid recanalization;	—

Secondary

Measure	Time frame
Lp-PLA2;polyunsaturated fatty acids;TR;gonadal hormone;	—

Countries

China

Contacts

Public ContactGang Peng

The Second Affiliated Hospital of Nanjing Medical University

18258215825@163.com+86 18951767529

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026