chemotherapy associated dyspepsia syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) between 18-75 ages; 2) patients with primary tumor after operation; 3) patients with platinum anticancer drug, and the KPS score >70; 4) patients with standard dose of anisetron/ondansetron to prevent vomiting; 5) informed written consent.
Exclusion criteria
Exclusion criteria: 1) subjects who suffered from gastrectomy; 2) subjects who suffered from unconscious, aphasia, mental disorders, dementia, and long-term bedridden that they couldnt provide detailed medical history; 3) subjects with a history of brain edema, the symptoms of primary or secondary brain tumors and increased intracranial pressure and / or brain metastases; severe liver and kidney disease and heart, lung disease, bradycardia, psychosis, epilepsy, pregnant women and lactation women, II, III degree atrioventricular block; 4) subjects with skin allergy; 5) subjects who took medications focusing on relieving dyspepsia symptoms (such as prokinetics, antidepressants, anxiolytics or TCM herbs) before starting treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Global Overall Symptom scale, GOS;Specific symptom subtype;The quality of life in dyspepsia (QoLD) questionnaire;EORTC QLQ-C30;Gastric accommodation;gastric transit time;Heart rate variability;Blood collection for ghrelin analysis;Blood collection for peptide YY analysis; | — |
Countries
China
Contacts
The 1st Affiliated Hospital of Xi'an Jiaotong University