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Association of blood donor age with prognosis of blood transfusion patients in SICU: a multicenter randomized controlled trial

Association of blood donor age with prognosis of blood transfusion patients in SICU: a multicenter randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900022057
Enrollment
Unknown
Registered
2019-03-22
Start date
2019-04-01
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

blood transfusion

Interventions

young donor group:transfused with blood components from 45 years male donors

Sponsors

Shaanxi Corps Hospital of Chinese People’s Armed Police Forces
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients in SICU with homologous blood transfusion; 2. Patients undergoing major surgeries with the predicting volume of blood transfusion greater than 1000mL(RBC+cryoprecipitate+frozen plasma);3. Aged 18 to 70 years.

Exclusion criteria

Exclusion criteria: 1. hematopathy; 2. requiring chronic blood transfusion; 3. patients with cancer undergoing conservative treatment; 4. being not enrolled into the study before admitted to SICU and simultaneously having been underwent homologous blood transfusion; 5. pre-existing pulmonary infection or bloodstream infection before being admitted to SICU; 6. after <3 d stay in SICU transferred to general ward; 7. autologous blood transfusion; 8. hematopoietic stem cell transplantation; 9. solid organ transplantation; 10. single-donor platenets inevitably used, but the donor age being not consistent with that of the previous blood components.

Design outcomes

Primary

MeasureTime frame
28-d mortality;length of stay in SICU;

Secondary

MeasureTime frame
infection rate in SICU;

Countries

China

Contacts

Public ContactXianfei Zeng
mumufly@126.com+86 13488356245

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026