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Intubated versus non-intubated with spontaneous breathing general anesthesia for the single-hole thoracic wedge resection and pulmonary lobectomy of Video-Assisted Thoracoscopic Surgery: A randomized controlled trial

Intubated versus non-intubated with spontaneous breathing general anesthesia for the single-hole thoracic wedge resection and pulmonary lobectomy of Video-Assisted Thoracoscopic Surgery: A randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900022020
Enrollment
Unknown
Registered
2019-03-20
Start date
2019-03-31
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thoracic disease

Interventions

N group:Paravertebral nerve block, laryngeal mask, spontaneous breathing
I group:General anesthesia with intubation

Sponsors

Zhejiang Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Preoperative bronchoscopy and puncture pathology for lung cancer; 2. Aged 18 and 75 years; 3. ASA physical Status I to II;Mallampatis I to II; 4. Patients have signed the informed consent before surgery and accepted the procedure voluntarily. 3. Patients

Exclusion criteria

Exclusion criteria: 1. With CT lymph node metastasis; 2. Patients with central nervous system diseases, strokes, mental disorders, patients who are unable to cooperate well, have alcohol dependence or long-term use of sedative and hypnotic drugs; 3. Heart, liver, kidney function severely damaged patients (NYHA III or IV, ALT, AST more than 1.5 times the upper limit of normal, Cr exceeds the upper limit of normal); 4. Patients with blood system diseases or coagulation disorders; 5. Pulmonary infection, poor lung function (FEV1.0 30kg/m2, or patients with myasthenia gravis; 9. Patients with a history of allergy to anesthetics; 10. Other surgeons/ anaesthesiologists regard it as a contraindication.

Design outcomes

Primary

MeasureTime frame
Glottal injury incidence;sore throat after operation;hoarse voice;cough after operation;hoarse voice;Lung collapse score;Intraoperative cough;pulmonary complications after surgery;

Secondary

MeasureTime frame
recovery time after anesthesia;pain score;hospital stay;introperative changing to intubate;first time to get off the bed;bloodstain on the laryngeal mask or tube;

Countries

China

Contacts

Public ContactLian Yanhong

Zhejiang Cancer Hospital

yanhong_lian@163.com+86 13957119583

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026