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Safety and effectiveness of intrathecal dexmedetomidine after spinal anesthesia for cesarean section: A randomized controlled trial

Safety and effectiveness of intrathecal dexmedetomidine after spinal anesthesia for cesarean section: A randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900022019
Enrollment
Unknown
Registered
2019-03-20
Start date
2019-04-01
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section

Interventions

B group:bupivacaine 9 mg (1.5 ml) i,t.
BF group:bupivacai7.5 mg+ fentanal 20 ug i.t.
BD group:bupivacaine 7.5mg + dexmedetomidine 5ug i.t.

Sponsors

Feng Xian People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 36 Years

Inclusion criteria

Inclusion criteria: puerpera with history of cardiac, respiratory, hepatic or renal disease, long history of taking analgetics or sedative, pregnant complications, with contraindications for spinal anesthesia, allergy to the study drugs, Participation in other drugs clinical trials during the past 3 months.

Exclusion criteria

Exclusion criteria: puerpera with history of cardiac, respiratory, hepatic or renal disease, long history of taking analgetics or sedative, pregnant complications, with contraindications for spinal anesthesia, allergy to the study drugs, Participation in other drugs clinical trials during the past 3 months.

Design outcomes

Primary

MeasureTime frame
concentration of dexmedetomidine in maternal blood;concentration of dexmedetomidine in fetal umbilical cord blood;

Secondary

MeasureTime frame
vital sign;adverse reaction;comfortable level of puerpera;the onset and offset time of spinal anesthesia;VAS score of analgesia;apgar score of neonatal;

Countries

China

Contacts

Public ContactLi Yumei

Affiliated hospital of Xuzhou medical university

519120189@qq.com+86 15862197126

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 26, 2026