Coronary atherosclerotic heart disease
Conditions
Interventions
Protective lung ventilation group:Protective lung ventilation
Conventionnal lung ventilation group:Conventionnal lung ventilation
Sponsors
Department of Anesthesiology, Peking University Third Hospital, Beijing
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The patient going to have selective small incision coronary artery bypass grafting under general anesthesia; 2. ASA grade I~III; 3. Expected survival time >3 months; 4. Can cooperate to observe adverse events and effects; 5. The patient or his legal representative signs a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. BMI> 40 kg/m2; 2. Patients with a history of pulmonary surgery or respiratory insufficiency, pulmonary infection, active asthma; 3. Chronic renal insufficiency (serum creatinine > 200 µmol/L); 4. Hepatic insufficiency (Child-Pugh grade B or above); 5. Hemodynamically unstable; 6. The patient has undergone long-term hormonal therapy or is in pregnancy; 7. Progressive neuromuscular disease; 8. The body temperature is above 38 degree C or there are obvious clinical infections that can affect clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygenation index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complication rate;levels of perioperative serum inflammatory factors; | — |
Countries
China
Contacts
Public ContactXu Mao
Department of Anesthesiology, Peking University Third Hospital, North Garden Rd.,Haidian District Beijing ,P.R.China
Outcome results
None listed