Diabetes
Conditions
Interventions
1:nerve block Group
2:nerve block+Dexmedetomidine
Sponsors
First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ASA I-III, cardiac function 1-3, male or female, knee replacement, diabetic patients (a random venous plasma glucose concentration =11.1 mmol/l or fasting blood glucose concentration =7.0 mmol/l (whole blood = 6.1 Methyl alcohol concentration =11.1 mmol/l and 75g two hours after anhydrous glucose in oral glucose tolerance test (OGTT)).
Exclusion criteria
Exclusion criteria: 1) Block can not be performed for various reasons; 2) Patients with coagulation dysfunction or receiving anticoagulation therapy; 3) Persons with a history of upper limb nerve injury or phrenic nerve injury; 4) Compound injury; 5) Preoperative Pulse Oxygen Saturation(SPO2)180 mmHg or diastolic blood pressure>110 mmHg) 7) Uncontrolled coronary heart disease, valvular heart disease and arrhythmia before operation; 8) Any reason that causes nerve block impossible to be performed (e.g. local infection at puncture site, swelling, unable to change position, etc.); 9) Fail to communicate or cooperate (mental retardation, Alzheimer, Parkinson, etc.); 10) Be allergic to ropivacaine or has other contraindications for nerve block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative NRS score;Postoperative motor score;Postoperative sensory score;Perioperative opioid use; | — |
Countries
China
Contacts
Public ContactChen Ke
First Affiliated Hospital of Anhui Medical University
Outcome results
None listed