Coronary Chronic Total Occlusion
Conditions
Interventions
Gold Standard:Invasive Coronary Angiography,ICA
Magnetic 
Resonance 
Imaging,CMR
Sponsors
Zhongshan Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with suspected or confirmed CTO: Coronary angiography showed total occlusion of one or more coronary arteries with TIMI 0 or 1 grade of forward flow lasting for more than 3 months; 2. No coronary revascularization before baseline CMR imaging and no complication with other cardiovascular diseases; 3. PCI was performed within 1 week of baseline CMR examination.
Exclusion criteria
Exclusion criteria: 1. Acute coronary syndrome occurred within 3 months; 2. Taking coffee stimulants within 24 hours before CMR; 3. Image quality is not competent for diagnosis and the informed consent is withdrawn by the subject; 4. ATP allergy or intolerance (severe asthma, conduction block, etc.), Gd contrast agent allergy; 5. Severe patients with malignant arrhythmia, acute myocardial infarction, severe cardiac insufficiency, instability of vital signs, renal insufficiency or glomerular filtration rate < 30 ml/min; 6. Contraindicated or intolerant patients with conventional MR examination: patients with cardiac pacemaker implantation, nerve stimulator, artificial metal valve, insulin pump, aneurysm clip, inner ear implantation, metal prosthesis implantation, severe fever, epilepsy, claustrophobia, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Myocardial Perfusion Reserve;Left Ventricular Function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Seattle Angina Quantitative Table;Major adverse cardiac events; | — |
Countries
China
Contacts
Public ContactMengshu Zeng
Outcome results
None listed