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A prospective, randomized controlled, single-center clinical trial: comparison of the clinical benefits for non-small cell lung cancer (NSCLC) patients between the different volume of pleural lavage fluid following video-assisted thoracoscopic lobectomy and systematic lymph node dissection

A prospective, randomized controlled, single-center clinical trial: comparison of the clinical benefits for non-small cell lung cancer (NSCLC) patients between the different volume of pleural lavage fluid following video-assisted thoracoscopic lobectomy and systematic lymph node dissection

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021950
Enrollment
Unknown
Registered
2019-03-17
Start date
2019-04-01
Completion date
Unknown
Last updated
2019-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary disease

Interventions

1:500 ml pleural lavage fluid
2:2000 ml pleural lavage fluid

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 to 75 years; 2. Patients undergoing VATS lobectomy and SLND; 4. ASA scores I-II grade; 5. Had essential complete materials such as clinical staging of lung cancer and medication; 6. Willing to participant after reading and signing an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Time for smoking cessation <2 weeks; 2. Preoperative hydrothorax of patients was predominant; 3. Patients were pregnant or breastfeeding women; 4. Patients with preoperative severe mental illness; 5. Patients with preoperative gastrointestinal or blood system disease; 6. Patients underwent cardiac ischemia; 7. Patients received preoperative radiotherapy or neoadjuvant chemotherapy; 8. The investigator judges that the patient is not suitable for inclusion in the trial.

Design outcomes

Primary

MeasureTime frame
the plasma level of leukocytes on 1-3 postoperative days;the plasma level of neutrophils on 1-3 postoperative days;Incidence of surgical complications;

Secondary

MeasureTime frame
Overall survival;3-year recurrence-free survival rate after operation;

Countries

China

Contacts

Public ContactChengwu Liu
jianzhouscu@foxmail.com+86 18780216171

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026