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Stool DNA Testing for opportunistic screening of High-risk Colorectal Cancer population

Stool DNA Testing for opportunistic screening of High-risk Colorectal Cancer population

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021947
Enrollment
Unknown
Registered
2019-03-17
Start date
2019-03-04
Completion date
Unknown
Last updated
2019-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

Gold Standard:Histopathological diagnosis of colorectal cancer to be the gold standard
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Sponsors

The Sixth Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 100 Years

Inclusion criteria

Inclusion criteria: (1) fecal occult blood was positive; (2) first-degree relatives had a history of colorectal cancer; (3) previous history of intestinal adenomas; (4) history of cancer; (5) changes in defecation habits; (6) any two of the following: chronic diarrhea, chronic constipation, mucus blood stool, chronic appendicitis or appendectomy, chronic cholecystitis or cholecystectomy, long-term mental depression, alarm signals (hematuria, blackstool, anemia, etc.) Weight loss and other colorectal cancer alarm symptoms).

Exclusion criteria

Exclusion criteria: 1. Patients who failed to complete fecal genetic testing, fecal occult blood test, and colonoscopy; 2. Patients who underwent colonoscopy and fecal genetic testing and fecal occult blood tests.

Design outcomes

Primary

MeasureTime frame
Stool DNA Testing;colonoscopy;SPE, SEN, ACC, AUC of ROC;

Secondary

MeasureTime frame
Fecal Immunochemical Test;

Countries

China

Contacts

Public ContactPeng Tieli

Department of Gastroenterology, The Sixth Affiliated Hospital of Guangzhou Medical University

pengtl@163.com+86 18998981585

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026