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Application of MRI study for brain structure and function of non-syndromic cleft lip and palate in treatment decision-making of cleft lip and palate

Application of MRI study for brain structure and function of non-syndromic cleft lip and palate in treatment decision-making of cleft lip and palate

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021937
Enrollment
Unknown
Registered
2019-03-16
Start date
2017-01-01
Completion date
Unknown
Last updated
2019-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nonsyndromic cleft lip and palate

Interventions

Case series:Nil

Sponsors

Beijing Stomatological Hospital Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Children (5-10 years old) and adults (18-40 years old) with NSCL/P are children with cleft palate (= 1 year); 2. Hearing test, intelligence test is normal; 3. right-handed; 4. Normal educational environment and growing environment background; 5. The articulation of articulation in NSCL/P patients with speech disorder was significantly higher than that in patients with speech disorder; 6. Informed consent.

Exclusion criteria

Exclusion criteria: 1. Diseases other than cleft lip and palate that affect test results ; 2. a central nervous system disease such as epilepsy Patients with severe cognitive impairment (MMSE screening score = 9); 3. Can't cooperate with the evaluation, examination and treatment of this test; 4. with taboo of magnetic resonance examination; 5. Other situations where the researchers do not think it is appropriate to take part in.

Design outcomes

Primary

MeasureTime frame
3DT1, DKI, Resting state fMRI;

Countries

China

Contacts

Public ContactRenji Chen

Beijing Stomatological Hospital Capital Medical University

chenrenji@126.com+86 13501216911

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026