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Histone demethylase LSD1/KDM1A as a potential biomarker in intracranial aneurysm

Histone demethylase LSD1/KDM1A as a potential biomarker in intracranial aneurysm

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021936
Enrollment
Unknown
Registered
2019-03-16
Start date
2017-03-06
Completion date
Unknown
Last updated
2019-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain naeurysm

Interventions

Group 1:Stent mesh method (SM)
Group 2:Stent monitoring deployment (SJD)
Group 3:Scaffold monitoring semi-deployment (SJS)

Sponsors

The First Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: The subjects were found with headaches without neurological deficits. IAs were confirmed by intra-arterial digital subtraction angiography (DSA), magnetic resonance angiography (MRA) and computed tomographic angiography (CTA). Glasgow Outcome Scale (GOS) was used for evaluating IA(16) and divided into five grades: dead, vegetative state, severe disability, moderate disability and good recovery with scores 1, 2, 3, 4 and 5, respectively(17). Patients had IAs within 1 year, and the patients or their care-givers signed an informed consent document indicating that they wanted to participate in the present experiment.

Exclusion criteria

Exclusion criteria: The patients would be excluded if they had the following complications: ruptured aneurysm or hemodynamically significant cerebral vasospasm, family history of IAs and or intracranial hemorrhage, undergoing surgical procedure or trauma within one month before the present experiment, platelet count 70 yr.

Design outcomes

Primary

MeasureTime frame
size of brain aneurysm;

Countries

China

Contacts

Public ContactHonglei Wang

The First Hospital of Jilin University

wanghongleimd@163.com+86 17390912089

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026