Hemiplegic cerebral palsy
Conditions
Interventions
1:CIMT+rTMS sham
2:CIMT+rTMS
blank control:CIMT
Sponsors
Guangzhou Women and Children's Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Diagnostic and classification criteria for hemiplegic cerebral palsy; (2) Aged 2-15 years old; (3) MACSI-III; (4) From the full flexion position, the wrist joint extension is =20 degrees, and the metacarpophalangeal joint is =10 degrees; (5) The difference between the scores of the overall evaluation scale of the hand and the hand function is 20%-80%; (6) Have a certain cognitive ability, can understand simple instructions, parents can cooperate with research and sign consent.
Exclusion criteria
Exclusion criteria: (1) suffering from other diseases not related to cerebral palsy; (2) Fixed contracture or deformity affecting the functional use of the hand; (3) severe hemiplegia (manual ability classification system IV or V or <20 degree finger/wrist extension) or major dystonia; (4) Children with epilepsy or severe sensory or visual problems; (5) TMS contraindications; (6) taking a drug that reduces muscle tone within 3 months before treatment, has received botulinum toxin injection in the last 6 months, or is ready to receive botulinum toxin type A during the study period; Received CIMT in the past 6 months; (7) The upper limb of the affected side has undergone orthopedic surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Melbourne Assessment 2;MT?MEP?Amplitude and latency,CMCT;(Motion threshold, motion evoked potential amplitude and latency, central conduction time); | — |
Secondary
| Measure | Time frame |
|---|---|
| SCUES;Nine hole test;MAS;AROM;Infant - junior high school students social life ability scale;GAS,Goal Attainment Scale;fMRI?DTI; | — |
Countries
China
Contacts
Public ContactQian-Wen WU
Guangzhou Women and Children's Medical Center
Outcome results
None listed