bronchial asthma
Conditions
Interventions
treatment group:ICS/LABA+Yi-Qi DecoctionBu-Shen-
Sponsors
Pu’er Hospital of traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18-75 years at the time of selection, regardless of gender; (2) Patients diagnosed as bronchial asthma by modern medicine, whose symptoms relieve and signs disappear after acute attack and reach the pre-attack level; (3) The average number of acute exacerbations in the past two years was more than 2 times per year; (4) TCM syndrome differentiation of lung and kidney qi deficiency; (5) Subjects will participate in the study voluntarily and have signed the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with bronchiectasis, active pulmonary tuberculosis, pulmonary infection, pulmonary interstitial fibrosis, pneumothorax, pleural effusion, pulmonary embolism, or neuromuscular diseases affecting respiratory motor function; (2) Patients who need long-term oral glucocorticoid or more than 3 kinds of asthma control drugs recommended by the long-term use guidelines; (3) Women who are pregnant or plan to become pregnant or lactating; (4) Patients with malignant tumors and blood diseases; (5) Have participated in the clinical trials of other drugs within 3 months; (6) Patients with severe cardiac, liver and renal function impairment (cardiac function level 3 ~ 4, ALT and/or AST exceeding 1.5 times of the normal upper limit, Cr exceeding the normal upper limit); (7) Patients suffering from rheumatic immune diseases and adrenal cortical dysfunction who need hormone and immunosuppressant; (8) Patients with fire flourishing syndrome of Yin deficiency identified by TCM; (9) Other conditions considered by the researcher not suitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of acute exacerbations;Duration and degree of attack;peak expiratory flow (PEF);the average daily diurnal variation rate;Fractional exhaled nitric oxide (FENO); | — |
Secondary
| Measure | Time frame |
|---|---|
| ACT score;Quantitative scoring of TCM syndromes;Peripheral blood inflammatory markers;Inflammatory markers in induced sputum;HPA axis related markers in plasma;HPA axis related markers in saliva; | — |
Countries
China
Contacts
Public ContactSu Mingyue
Outcome results
None listed