goal-directed fluid therapy
Conditions
Interventions
Control:Conventional fluid therapy
GDFT group :Flo-Trac/Vigileo system management
Sponsors
The First Affiliated Hospital of Chengdu Medical College
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. ASA I-III,Patients undergoing elective surgery; 2. Elderly patients who aged above 65 years; 3. Patients and their families are willing to participate in the study and sign the consent form.
Exclusion criteria
Exclusion criteria: 1. Preoperative examination confirmed the existence of cognitive impairment; 2. Patients with severe heart disease; 3. Anxiety and other mental disorders; 4. Suffering from head trauma; 5. Patients with apoplexy sequelae, senile dementia, cerebral hemorrhage and other vital organ failure suffer from certain diseases; 6. Drug or other substance abusers who interfere with the assessment of cognitive function; 7. Patients with severe neurological defects, such as aphasia, agnosia, severe hemiplegia and audio-visual impairment; 8. Allen test of left radial artery (+).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| glialfibrillaryacidicprotein,GFAP;S100ß;TNF-a; | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-1;IL-6;blood gas analysis; | — |
Countries
China
Contacts
Public ContactDong Shuhua
Outcome results
None listed