Ovarian Cancer
Conditions
Interventions
test group:Selective cleanup of lymph nodes
control group:Systemic cleanup of lymph nodes
Sponsors
Shengjing Hospital affiliated to China Medical University
Eligibility
Sex/Gender
Female
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Subjects aged 60 to 75 years. 2. Initial surgical treatment (general staging or cytoreductive surgery) that has been histologically diagnosed and standardized. 3. Postoperative stage is II to IVA (segment according to 2014 FIGO staging standard). 4. Give the greatest degree of tumor cytoreductive surgery as far as possible to achieve R0 or R1. 5. The pathological type is epithelial ovarian cancer, fallopian tube cancer or peritoneal cancer. 6. For patients with stage III to IV who have large tumors and are unable to achieve satisfactory tumor reduction or have a high risk of surgery, neoadjuvant chemotherapy may be considered, followed by intermittent cytoreductive surgery. 6) At least 4-6 courses of platinum-based chemotherapy after surgery. 7) KPS physical status score = 60. 8) The estimated survival time is =12 weeks. 9) Complete objective imaging examinations such as abdominal CT/MR/PETCT before surgery. 10) Subjects have signed an informed consent form prior to conducting a specific study operation or evaluation and are willing to receive treatment and follow-up according to the protocol.
Exclusion criteria
Exclusion criteria: 1. Severe coagulation mechanism disorder, bleeding tendency. 2. The subject has any serious and/or pre-existing unstable disease (eg, uncontrolled infection, etc.), mental illness or safety of the subject, signing informed consent or compliance with the protocol. The situation of influence. 3. There are other contraindications for surgery and chemotherapy. 4. The investigator believes that it is not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-year survival rate;5-year survival rate; | — |
Countries
China
Contacts
Public ContactXiuqin Li
Department of Gynecology, Shengjing Hospital affiliated to China Medical University
Outcome results
None listed