Acute Postoperative Pain
Conditions
Interventions
Morphine group:The first dose of morphine 0.1 mg/kg was given 10 minutes before the operation, followed by intravenous analgesia pump. Analgesic formula: morphine is 0.1mg/kg (2ml) per pressing, the t
Oxycodone group:The first dose of Oxycodone 0.1 mg/kg was given 10 minutes before the operation, followed by intravenous analgesia pump. Analgesic formula: morphine is 0.1mg/kg (2ml) per pressing, the
Sponsors
The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
Female
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Female, ASA Class I-II; 2. Aged 20-55 years; 3. BMI 18-24 kg/m2; 4. Liver, kidney and lung function were normal; 5. Hemoglobin >80g/L; 6. Laparoscopic DIE resection was planned.
Exclusion criteria
Exclusion criteria: 1. Alcohol and drug addiction; 2. Respiratory and circulatory system and liver and kidney diseases; 3. Long-term use of diazepam; 4. Difficulty of tracheal intubation; 5. With a history of hypertension, diabetes mellitus and coronary heart disease; 6. Intraoperative severe bleeding requiring blood transfusion; 7. pairs of drug allergic patients such as oxycodone and morphine; 8. Surgery requires removal of other organs such as intestine, bladder or ureter; 9. Conversion to laparotomy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Morphine consumption;Oxycodone consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| visualized analgesic score;fentanyl consumption;blood pressure;Pulse oxygen saturation;Respiratory frequency;heart rate; | — |
Countries
China
Contacts
Public ContactYunsheng Li
The First Affiliated Hospital, Sun Yat-Sen University
Outcome results
None listed