Delirium
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) unilateral total hip arthroplasty; 2) combined spinal and epidural anesthesia; 3) ASA grade I-III; 4) postoperative analgesia; 5) older than 65 years.
Exclusion criteria
Exclusion criteria: 1) Existing cognitive impairment (Mini-Mental State Examination (MMSE) less than 20 points); 2) History of neurological and psychiatric disorders with AD, stroke and psychosis; 3) ASA IV-V; 4) severe Vision or hearing impairment, illiterate; 5) allergic to any drug in the study; 6) unless the steroidal anti-inflammatory drug, COX-2 inhibitor or acetaminophen, daily taking painkillers; 7) drug or alcohol abuse History; 8) can not cooperate, do not want to comply with the protocol or procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| s-100 protein;TNF-a;IL-1;IL-6;IL-8;C-reactive protein; | — |
Countries
China
Contacts
Chongqing Traditional Chinese Medicine Hospital