bronchial asthma
Conditions
Interventions
Experimental group:ICS/LABA+Bu-Shen-Yi-Qi Decoction
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Repeated attacks of wheezing, chest tightness, shortness of breath or cough, mostly due to exposure to allergens, physical and chemical sounds, scattered stimulation, viral infection of the upper respiratory tract, sports, etc.; (2) It can be heard in both lungs and wheeze mainly in the exhalation phase or diffuse, and extend in the exhalation phase; (3) The above symptoms and signs can be relieved by themselves or after treatment; (4) Wheezing, chest tightness and cough caused by other diseases were excluded; (5) Patients with relatively complete medical records should have at least the contents of symptoms, syndrome type/treatment, prescriptions, dosage, etc.
Exclusion criteria
Exclusion criteria: (1) Patients with bronchiectasis, active pulmonary tuberculosis, pulmonary infection, pulmonary interstitial fibrosis, pneumothorax, pleural effusion, pulmonary embolism, or neuromuscular diseases affecting respiratory motor function; (2) Patients who need long-term oral glucocorticoid or more than 3 kinds of asthma control drugs recommended by the long-term use guidelines; (3) Women who are pregnant or plan to become pregnant or lactating; (4) Have participated in the clinical trials of other drugs within 3 months; (5) Patients with severe cardiac, liver and renal function impairment (cardiac function level 3 ~ 4, ALT and/or AST exceeding 1.5 times of the normal upper limit, Cr exceeding the normal upper limit); (6) TCM identifies patients with Yin deficiency and fire flourishing syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ACT score;Acute exacerbation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quantitative score of asthma symptoms;lung function;The use of Reliever;Frequency of acute exacerbations;Peripheral blood inflammatory markers;Quality of life questionnaire; | — |
Countries
China
Contacts
Public ContactDong Jingcheng
Huashan Hospital, Fudan University
Outcome results
None listed