Bronchopulmonary Dysplasia
Conditions
Interventions
Group 1:Hydrocortisone
Group 2:receive the equal volume saline
Sponsors
Southwest Medical University Affiliated Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1) Gestational age 26+0 to 30+6 weeks and birth weight 0.3 or .non-invasive ventilation support or nasal cannula with FiO2 > 0.21.
Exclusion criteria
Exclusion criteria: Exclusion criteria including any of the following conditions: 1) Need of invasive ventilation support at 28th day of life. 2) Congenital malformations affecting pulmonary function (e.g. congenital surfactant protein deficiencies, congenital diaphragmatic hernia) or increasing the risk of death or adverse neurodevelopmental outcome (e.g. congenital cerebral malformations, congenital hydrocephalus). 3) Chromosomal defects (e.g. trisomy 13, 18, 21). 4) Severe infection less than 7 days before randomization (Late-onset sepsis/ meningitis confirmed by positive blood culture; bacterial pneumonia, confirmed by positive tracheal culture; NEC).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is to assess survival without moderate or severe BPD at PMA 36 weeks.; | — |
Countries
China
Contacts
Public ContactXiaoping Lei
Southwest Medical University Affiliated Hospital
Outcome results
None listed