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Preoperative injection of nano-carbon suspension combined with surgical technique of lymph node dissection around the inferior mesenteric artery with preservation of the left colic artery in patients with colorectal cancer undergoing NOSES( natural orifice specimen extraction)

Preoperative injection of nano-carbon suspension combined with surgical technique of lymph node dissection around the inferior mesenteric artery with preservation of the left colic artery in patients with colorectal cancer undergoing NOSES( natural orifice specimen extraction)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021804
Enrollment
Unknown
Registered
2019-03-10
Start date
2018-09-01
Completion date
Unknown
Last updated
2019-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

early group:Preserve blood vessels in the left colon
medium group:Preserve blood vessels in the left colon
late group:Preserve blood vessels in the left colon

Sponsors

Wenzhou Central Hospital, Zhejiang Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
80 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Patients with sigmoid colon and rectal cancer were diagnosed by colonoscopy and biopsy before operation; 2. Preoperative imaging showed that the diameter of tumors was less than 4 cm; 3. Carbon nanoparticles suspension was injected the lower edge of the lesions under routine colonoscopy one day prior to operation,Natural orifice specimen extraction surgery (NOSES) after laparoscopic colorectal resection (LCRR) is agreed by the patients.

Exclusion criteria

Exclusion criteria: 1. The patients could not tolerate operation; 2. Preoperative neoadjuvant radiation or chemoradiation therapy; 3. The patients need emergency operations; 4. Imaging findings suggest that the tumors infiltrate into the periphery or stage IV cancer and stoma creation.

Design outcomes

Primary

MeasureTime frame
the number of lymph nodes;

Secondary

MeasureTime frame
operation time;bleeding amount;conversive rate of operation;

Countries

China

Contacts

Public ContactWang Zhonglin

Wenzhou Central Hospital, Zhejiang Province

phl15507@163.com+86 13968874566

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026