Type 2 Diabetes-Associated Periodontitis
Conditions
Interventions
Group 1:SRP, adjuvant medication after scaling
Group 2:SRP,adjuvant medication after subgingival scaling
Group 3:SRP
Sponsors
Weifang Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Chronic periodontitis (CP): According to the new international classification of periodontal diseases in 1999 and Page's recommended diagnostic criteria, the diagnosis was moderate or severe CP. There were not less than 16 residual teeth (excluding the third molar), at least 4 teeth with periodontal pocket depth (>5 mm) and attachment loss (>4 mm). (2) Type 2 diabetes mellitus: according to the WHO diagnostic criteria for diabetes in 1999, type 2 diabetes mellitus was diagnosed; the course of disease was at least one year; GHbAlc was less than 11.00%, stable, without serious cardiovascular complications and other systemic diseases of diabetes mellitus; there was no change in recent medication, diet and exercise habits.
Exclusion criteria
Exclusion criteria: (1) There was a history of antibiotics, non-steroidal anti-inflammatory drugs or hormone drugs in 6 months; (2) There was a history of periodontal treatment or surgical operation within 6 months; (3) Systemic diseases other than diabetes, such as cardiovascular diseases, rheumatoid diseases, endocarditis, nephrotic syndrome, malignant tumors, etc.; (4) Pregnant or lactating women; (5) The general condition is poor and the patients can not accept periodontal examination and/or treatment. (6) Smokers; (7) Those who cannot return on schedule.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical attachment level;Probing depth;HbA1c; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bleeding Index; | — |
Countries
China
Contacts
Public ContactJi Honghai
Outcome results
None listed