Prospective study for the effect of periodontal corticotomy and regenerative surgery in the prevention and treatment of periodontal soft and hard tissue defects in patients with severe malocclusion

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900021778

Enrollment

Unknown

Registered

2019-03-09

Start date

2019-03-05

Completion date

Unknown

Last updated

2019-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malocclusion

Interventions

experimental group:periodontal regenerative surgery combined with minimally invasive ultrasound bone corticotomy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18-40 years, systemic healthy; 2. Skeletal class III malocclusion with the need of orthodontic and orthognathic treatment; 3. Periodontally healthy, or controlled gingivitis or mild periodontitis; 4. The thickness of labial alveolar bone in upper and lower anterior teeth is less than 0.5mm or the width of labial-lingual base bone in apical region of lower anterior teeth is less than the width of root by cone-beam CT imaging observation; 5. Clinical examination showed that the root appearance of upper and lower anterior teeth is obviously exposed, and the root protrusion could be palpable; 6. Agreement in participating in the research.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Systemic disease or tumors; 3. Acute inflammation of oral cavity and maxillofacial region; 4. Smoking addicts (>10 cigarettes per day); 5. Patients with moderate to severe periodontitis or uncontrolled gingivitis or mild periodontitis; 6. Cleft lip and palate or maxillofacial abnormalities; 7. Patients with mental illness or other reasons who cannot cooperate with the treatment.

Design outcomes

Primary

Measure	Time frame
Periondontal Biotype;Width of keratinized gingival;Sagital root position;Root length;Lingual and labial Vertical bone level;Lingual and labial Alveolar bone thickness;Lingual and labial Alveolar bone area;basic cephalometric items;fenestration and dehiscence;width of periodontal ligament;Gingival thickness;Thickness of buccal-lingual periodontal tissues thickness;Three-dimensional morphology of periodontal soft tissues;Three-dimensinal morphology of alveolar bone crest gingiva;	—

Measure

Time frame

Periondontal Biotype;Width of keratinized gingival;Sagital root position;Root length;Lingual and labial Vertical bone level;Lingual and labial Alveolar bone thickness;Lingual and labial Alveolar bone area;basic cephalometric items;fenestration and dehiscence;width of periodontal ligament;Gingival thickness;Thickness of buccal-lingual periodontal tissues thickness;Three-dimensional morphology of periodontal soft tissues;Three-dimensinal morphology of alveolar bone crest gingiva;

—

Countries

China

Contacts

Public ContactXu Li

Peking University School and Hospital of Stomatology

xulihome@263.net+86 13621219600

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026