Stable Coronary Artery Disease
Conditions
Interventions
Experiment group:Taoren Honghua Jian
Control group:Taoren Honghua Jian placebo
Sponsors
Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnostic criteria for chronic stable coronary heart disease: (1) Has a history of myocardial infarction, treated by or without revascularization (percutaneous coronary intervention or coronary artery bypass grafting); (2) Coronary angiography or coronary CT showed that the diameter of at least one main branch of the coronary artery is narrowed by more than 50%, and was treated with or without revascularization; 2. The type of TCM syndrome is Qi stagnant and blood stasis; 3. Patients aged 18-70 years; 4. Patients who volunteer to participate in the study and sign the informed consent; 5. no pregnancy or have no plans of pregnancy or feeding women.
Exclusion criteria
Exclusion criteria: (1) myocardial infarction (MI) and other heart disease, such as severe neurosis, menopausal syndrome, hyperthyroidism, chest pain caused by cervical spondylosis; (2) with severe hypertension, severe cardiopulmonary insufficiency, severe arrhythmia, immune system diseases; (3) allergic constitution or allergic to Taoren Honghua Jian or has serious adverse reactions; (4) tumor and cancer patients; (5) mania, depression and other mental disorders; (6) has a history of infectious diseases such as tuberculosis, hepatitis b and HIV virus and other infectious diseases; (7) poor control of internal diseases such as diabetes, hyperlipidemia, respiratory infections, etc.; (8) with opioid analgesic, sedative hypnotic drug and alcohol abuse history; (9) with severe liver and kidney disease or kidney function damage serious (ALT and AST more than 1.5 times higher than normal limit, serum creatinine level is higher than 1.5 times bigger than the upper limit of normal); (10) with blood system disease patients, such as 1) hemoglobin < 9 g/dL and hemoglobin and red blood cell press < 30%; 2) white blood cell count < 3.0 x 10^9/L; 3) neutrophil count < 1.2.0 x 10^9/L; 4) the platelet count < 100 x 10^9/L, etc.; (11) adherence is poor, cannot meet the requirement.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| immune index;TCM syndrome score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Single symptoms of TCM curative effect analysis;Seattle angina questionnaire;MOS Sleep Scale;ECG;echocardiography; | — |
Countries
China
Contacts
Public ContactPing Liu
Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed