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Corneal biomechanical stability after epithelium removal and transepithelial corneal collagen crosslinking for keratoconus

Corneal biomechanical stability after epithelium removal and transepithelial corneal collagen crosslinking for keratoconus

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021768
Enrollment
Unknown
Registered
2019-03-08
Start date
2017-06-01
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Keratoconus

Interventions

Transepithelial corneal crosslinking group: none
epithelium removal corneal crosslinking group:Removal of corneal epithelium during operation

Sponsors

Hainan Ophthalmological Hospital of Zhongshan Ophthalmological Center of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Corneal topography showed progressive aggravation of keratoconus, and the maximum corneal curvature increased by more than 1.00D within 6 to 12 months. The maximum diopter of cornea > 45.00 D, astigmatism > 1.50 D, and corneal thickness > 400 um.

Exclusion criteria

Exclusion criteria: Patients do not meet the inclusion criteria or suffer from systemic organic diseases.

Design outcomes

Primary

MeasureTime frame
Corneal topography;Corneal biomechanics;Corneal endothelium count;—

Countries

China

Contacts

Public ContactZhong Xingwu

Hai'nan Ophthalmological Hospital of Zhongshan Ophthalmological Center of Sun Yat-sen University

zhongxwu@mail.sysu.edu.cn+86 13051119207

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026