Type 2 diabetes(Qi yin two deficiency heat syndrome)
Conditions
Interventions
Experimental group:Huang Huang drops sugar capsules, 6 tablets each time, 3 times a day, half an hour before the meal. Metformin hydrochloride tablets: The original daily dose remains unchanged, oral.
Control group:Simulated yellow sugar capsules, 6 at a time, 3 times a day, half an hour before the meal. Metformin hydrochloride tablets: The original daily dose remains unchanged, oral.
Sponsors
First Affiliated Hospital of Xiamen University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years, gender is not limited; 2. Patients with type 2 diabetes who meet the criteria for Western diagnosis of diabetes; 3. In line with the Chinese medicine Qi Yin two false heat syndrome; 4. Only treated with dimethyl diguanidine hydrochloride, and the dose is stable, not less than 4 weeks; 5. Poor control: Blood sugar[ 6.5 mmol/L = FPG(venous blood) = 10.0 mmol/L; 7.0 % HbA1c(glycated hemoglobin) = 8.0 %(based on the detection value of each center)]; 6. Subjects were informed and voluntarily signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Type 1 diabetes, gestational diabetes, type 2 diabetes and other special types of diabetes requiring insulin treatment; 2. Patients with acute complications of diabetes; 3. Combine serious heart and cerebrovascular diseases and serious primary diseases such as liver, kidney and hematopoietic system; 4. Allergies and allergies to known ingredients of drugs; 5. Pregnant and lactating women and those who have recent birth plans; 6. Long-term alcohol abuse, drug dependence, and mental illness; 7. Patients treated with oral Chinese medicine or proprietary Chinese medicine within 1 month before screening; 8. Those who had participated or were participating in clinical trials of other drugs within one month prior to the screening period of this study; 9. The researchers considered it inappropriate to participate in this clinical researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the treatment of hemoglobin glycosylated during the 12th weekend compared to the baseline period; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in fasting and postprandial 2H blood sugar per visit point;Treatment of changes in islet function in the 12th weekend compared to the baseline period(insulin release test, area under curve, insulin resistance index);Treatment of Chinese medicine syndrome on the 12th weekend compared with the baseline changes in curative effect;Quality of Life Scale for Treatment of Diabetes at the 12th Weekend;Symptoms, signs, disappearance, or clinical control.; | — |
Countries
China
Contacts
Public ContactYang shuyu
Xiamen University Affiliated First Hospital
Outcome results
None listed