Efficacy of granulocyte colony stimulating factor in the treatment of hepatic failure in children: A single-center, placebo-controlled, prospective clinical study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900021753

Enrollment

Unknown

Registered

2019-03-08

Start date

2019-11-01

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver failure

Interventions

Intervention group:G-CSF

control group:Conventional treatment

Eligibility

Sex/Gender

All

Age

0.4 Years to 17 Years

Inclusion criteria

Inclusion criteria: 1. Children diagnosed with liver failure; 2. Aged 4 months to 17 years.

Exclusion criteria

Exclusion criteria: 1. Allergy to G-CSF; 2. Malignant tumors or serious diseases of the blood system; 3. Definite uncontrolled bacterial infection; 4. Patients with other serious systemic diseases and mental diseases; 5. Recent or current participants in other clinical trials; 6. Children preparing for liver transplantation.

Design outcomes

Primary

Measure	Time frame
1 month survival rate;3 months survival;	—

Secondary

Measure	Time frame
Liver function;	—

Countries

China

Contacts

Public ContactChunbao Guo

Children's Hospital of Chongqing Medical University

guochunbao@foxmail.com+86 13032386618

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026