Non-Small Cell Lung Cancer
Conditions
Interventions
Study Group:Sublobectomy
Control Group:Lobectomy
Sponsors
Shanghai Chest Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years; 2. Preoperative thin-section computed tomography (TSCT) will fulfill all of the following conditions: Lesion size is less than 10 mm; 3. Preoperative clinical staging: T1aN0M0 (according to UICC2017-8thTNM staging); 4. R0 resectable in segmentectomy and wedge resections plus hilar/ mediastinal lymph node resection; 5. Preoperative FEV1.0>=1.5 L and >= 50% of the expected value; 6. Performance status of ECOG 0 or 1; 7. Preoperative ASA scoring (American society of anesthesiology) class I -III; 8. The patient agrees to participate in the trial and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Quit smoking <2 weeks; 2. Multiple ground glass nodules with suspect of multiple primary lung cancer; 3. TSCT shows that the lesion is located in the right middle lobe; 4. The lesion is located between two segments with possibility of combined segmental resection; 5. Pregnant or lactating women; 6. Serious mental illness; 7. With other malignant disease history within 5 years; 8. With the history of unstable angina or myocardial infarction within 6 months; 9. With the history of cerebral infarction or cerebral hemorrhage within 6 months; 10. With the history of sustained systemic corticosteroid therapy within 1 month; 11. Other unsuitable situations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 5-year Disease-Free Survival; | — |
Countries
China
Contacts
Public ContactQingquan luo/ Jia Huang
Shanghai Chest Hospital
Outcome results
None listed